员工动态

31-05-2023

Robustness and homeostasis in biological networks

报告人:王洋洋, University of Iowa

报告时间202362日下午3:30-4:30

报告地点:环境公司楼316

腾讯会议853-438-762

题目: Robustness and homeostasis in biological networks

摘要:Motor systems show an overall robustness, but because they are highly nonlinear, understanding how they achieve robustness is difficult. In many rhythmic systems, robustness against perturbations involves response of both the shape and the timing of the trajectory. This makes the study of robustness even more challenging. To understand how a motor system produces robust behaviors in a variable environment, we consider a neuromechanical model of motor patterns in the feeding apparatus of the marine mollusk Aplysia californica that operates within hard limits. We apply recently developed tools from variational analysis and phase reduction to explain in detail the robustness mechanism of the neuromechanical model against sustained external perturbations such as increased mechanical load during swallowing, varying sensory feedback gain, or muscle strengths. Homeostasis in other biological networks will also be discussed.

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